What is the difference in access between a CT-guided lung biopsy and a bronchoscopic biopsy?

• A. CT-guided biopsy uses endoscopic route through airways; bronchoscopic biopsy is percutaneous.
• B. CT-guided biopsy is percutaneous sampling from the chest wall; bronchoscopy obtains samples via the airways.
• C. Both access through the skin; CT-guided uses ultrasound guidance.
• D. CT-guided uses intravenous sampling; bronchoscopy uses percutaneous needle.

Answer: (B)

The main idea is the access route to the lung. A CT-guided lung biopsy uses a percutaneous approach—needle insertion through the skin and chest wall to reach a lesion, with CT helping guide the trajectory. Bronchoscopy, on the other hand, samples via the airways: a bronchoscope is passed through the nose or mouth into the trachea and bronchi, and tissue is taken through the bronchial tree.

This difference explains when each method is used: percutaneous sampling is often chosen for peripheral lesions that are difficult to reach from the airways, while bronchoscopy is favored for central lesions or when sampling within the bronchial tree itself is needed. The other statements mix up these routes or describe scenarios that don’t fit how these procedures access the lung.